Ophthalmic penetration of moxifloxacin

This work is published and licensed by Dove Medical Press Limited. Official Journal email alerts Get the latest issues delivered direct to your inbox Subscribe now. The 3-day group and the 1-hour group had 30 eyes each and the control group had 60 eyes. Conclusions The findings of this investigation reveal that topically administered moxifloxacin 0. There is also debate regarding potential deleterious effects of prophylactic use of antibiotics, including the potential acceleration of development of resistance, ocular toxicity, and alterations of the normal ocular flora to allow the growth of more virulent organisms. Techniques to reduce pathogens from the ocular surface include preparation of the skin and conjunctiva with povidone-iodine.

It is clear from the array of studies summarized in this report that moxifloxacin penetrates ocular tissues better two- to three-fold than gatifloxacin, ciprofloxacin, ofloxacin, or levofloxacin. Weekly Drug News Roundup. This material is provided for educational purposes only and is not intended for medical advice, diagnosis or treatment. To apply the eye drops: Tilt your head back slightly and pull down your lower eyelid to create a small pocket. Moxifloxacin is a fluoroquinolone flor-o-KWIN-o-lone antibiotic that fights bacteria in the body. Ophthalmic anti-infectives. Vigamox R : Instill 1 drop in the affected eye s 3 times a day.

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